รายงานการวิจัย

Signaling mechanisms of enhanced neutrophil phagocytosis and chemotaxis by the polysaccharide purified from Ganoderma lucidum

Chinese medical fungus, Ganoderma (G.) lucidum, has been a favorite remedy in oriental medicine for centuries. It was considered to maintain the vitality of human beings and to promote longevity (Shiao et al., 1994).

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Reishi polysaccharides induce immunoglobulin production through the TLR4-TLR2-mediated induction of transcription factor Blimp-1

The polysaccharides of Ganoderma lucidum (Reishi) possess immunomodulation activities; however, their mode of molecular action in regulating each ellular subset in the immune system is still not clear.

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Isolation and characterization of a new immunomodulatory protein, ling zhi-8 (LZ-8), from Ganoderma lucidium

A novel protein with mitogenic activity in vitro and immunomodulating activity in vivo has been isolated from the mycelial extract of an Oriental medicinal fungus, Ling Zhi (Ganoderma lucidium). This protein was named Ling Zhi-8 (LZ-8) and its biochemical and immunological properties are described

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GLIS- a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response

The mushroom Ganoderma lucidum (G. lucidum), a lamellaless basidio-mycetous fungus belonging to the family Polyporaceae (Leyss.ex Fr. Karst), known as ‘Lingzhi’ in China and ‘Reishi’ in Japan, has played an important role in Chinese traditional medicine for more than 4000 years.

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Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathway

In the oldest Chinese medical text, “Shen-Nong Ben Cao Jin,” Ganoderma species (a group of medical fungus) is recorded as the king of herbs.

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Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum

Ganoderma lucidum, a popular medicinal mushroom, has been widely used in traditional Chinese medicine in many Asian countries during the past two millennia.

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Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell
cycle arrest

Medicinal mushrooms have a long history of use in folk medicine. Ganoderma lucidum (G. lucidum) a basidiomycetes mushroom, is one of the most popular chemopreventive mushrooms in oriental countries.

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Ling Zhi-8 mediates p53-dependent growth arrest of lung cancer cells proliferation via the ribosomal protein S7-MDM2-p53 pathway

Ganoderma lucidum (Ling Zhi or Reishi), a medicinal fungus and mushroom, has long been used in traditional Chinese medicine (TCM) and in Asia for promotion of health and longevity as well as for the treatment of various diseases.

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Isolation and identification of C-19 fatty acids with anti-tumor activity from the spores of Ganoderma lucidum (reishi mushroom)

The reishi mushroom (literally “supernatural mushroom”) has been an important medicinal herb in traditional Chinese medicine for more than two millennia.

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Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells

Ganoderma lucidum (Fr.) Karst (Polyporaceae) is an important traditional Chinese medicinal mushroom used for several thousand years in China, Japan, and other countries.

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Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi)- results of a controlled human intervention trial

Lingzhi (Ganoderma lucidum) is a woody mushroom and popular medicinal herb, which is widely used in China and many other Asian countries

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Ganoderma atrum polysaccharide protects cardiomyocytes against anoxia-reoxygenation-induced oxidative stress by mitochondrial pathway

Cardiovascular disease is a leading cause of death worldwide and remains one of the major killers in modern society.
It can be initiated by multiple factors including ischemia/reperfusion injury

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Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum

Aging is one of the risk factors for various chronic diseases, including cancers, cardiovascular disease and neurodegenerative diseases.

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